In This Episode
In this edition of Proactive Longevity Academy, Dr. John Layke dives into the revolutionary science behind stem cells and exosomes, discussing how these powerful tools in regenerative medicine are helping to repair damaged tissue, promote longevity, and treat conditions from joint injuries to autoimmune diseases. He explores how stem cells regenerate and differentiate, while exosomes serve as guides, signaling cells to repair sites throughout the body. Gain insights into advanced treatments, like systemic infusions and targeted joint injections, and discover how they are shaping the future of healing and health span. This is an episode you won’t want to miss!
Questions Answered in This Episode
- How do stem cells and exosomes work together to help the body?
- How are stem cells and exosomes being used for joint repair, such as in knees?
- What are the benefits of stem cell infusions, and why might they be used in longevity treatments?
Dr. John Layke
Dr. John Layke is a highly regarded board-certified plastic and reconstructive surgeon, recognized for his expertise in both cosmetic surgery and regenerative medicine. As a co-founder of Beverly Hills MD, Dr. Layke is at the forefront of anti-aging and wellness, pioneering treatments like stem cell therapy and exosome applications to enhance both aesthetic and functional health. Known for his blend of artistry and scientific knowledge, Dr. Layke is dedicated to helping people look and feel their best, often sharing insights into the latest trends in regenerative medicine and longevity therapy.
A Glimpse of What You’ll Hear
- 00:41: Overview of stem cell function in the body.
- 01:45: Explanation of how exosomes work with stem cells in the healing process.
- 02:12: Insights into the use of stem cells and exosomes in joint repair.
- 02:30: Differences between systemic infusions and targeted injections.
- 03:19: Benefits of targeted, localized injections for injury treatment.
- 03:58: The role of infusions in promoting longevity.
- 05:15: How stem cell infusions support the body’s repair mechanisms.
Quotable Moments
- Dr. John Layke (00:41): “Stem cells act as a repair mechanism by renewing and differentiating, essential for replacing damaged cells.”
- Dr. John Layke (01:45): “Exosomes are the couriers, guiding stem cells to where they are needed most in the body.”
- Dr. John Layke (02:30): “Stem cells and exosomes have amazing potential, but localized injections can direct repair to specific injury sites.”
- Dr. John Layke (04:12): “Infusions of healthy cells can reset the body, offering a roadmap for DNA repair over time.”
Key Takeaways
- Stem Cells as Repair Tools: Stem cells self-renew and differentiate, making them essential for regenerative medicine.
- Exosomes as Cellular Guides: Exosomes direct stem cells to repair sites, enhancing the precision of therapies.
- Localized vs. Systemic Therapy: Localized injections improve treatment focus, while infusions offer whole-body renewal.
- Longevity Benefits: Healthy stem cell infusions can help repair age-related DNA damage, supporting overall health and vitality.
- Challenges in Regenerative Medicine: Though promising, systemic control of stem cell placement remains a primary focus for improvement.
Transcript
00:00
Dafne Canales
Welcome, everybody, to another episode of Proactive Longevity Academy. Today I have Dr. John Layke talking to us about stem cells and exosomes and why they’re such a hot topic in regenerative medicine.
00:13
Dr. John Layke
How are you doing, Dafne?
00:14
Dafne Canales
Doing great, thank you.
00:16
Dr. John Layke
So, listen, first of all, I’d love to thank all the listeners and viewers for sending in all of your feedback and emailing the questions, because ultimately, this is how we come up with the topics, and we want to answer what interests you. So keep them coming. We’ve got a really exciting topic here, and it’s something that we could speak volumes about. So without further ado, let’s take the first question.
00:41
Dafne Canales
All right, so how do stem cells and exosomes help the body? Like, how does regenerative medicine help the body?
00:50
Dr. John Layke
Stem cells function in the body by having unique abilities. They do two things: one is they self-renew, which means they can make more of the same type of cell, and they can also differentiate into specialized cells, allowing them to replace damaged or dead cells within a tissue, acting as a repair mechanism for the body. This makes them highly valuable in regenerative medicine, where the goal is to repair damaged tissue and organs by introducing new and healthy cells. Exosomes become really important because they’re responsible for cellular communication. Exosomes are tiny vesicles that carry all of the messaging, guiding stem cells on what to do and where to go.
01:45
Dr. John Layke
Ultimately, they attach to new stem cells, taking some of that information, and they can send new signals to existing cells. When these work synergistically, imagine they’re almost like the worker bees that head out from the hive to find the repair area and communicate with each other.
02:12
Dafne Canales
Okay. In regenerative medicine, we often talk about repair and sometimes about longevity. You mentioned joint repair, like in knees. Can you explain more about how exosomes and stem cells are used for joint repair?
02:30
Dr. John Layke
Definitely. When we look at two different therapies for stem cells and exosomes, we talk about infusions. One is in the blood—kind of a shotgun approach to infuse the system with healthy new cells and growth factors. We also target joints and specific injuries. The issue we have with stem cells and exosomes is that they have amazing potential, but we can’t quite control where they go yet. Localized injections, using ultrasound or fluoroscopic guidance, allow us to inject directly into the site—like tendons or cartilage. By delivering repair mechanisms immediately to the site, the repair process is much more efficient.
03:58
Dafne Canales
Thank you. And regarding longevity, what benefits do people see with infusions into the bloodstream?
04:12
Dr. John Layke
When we infuse healthy, new cells, they help repair accumulated genetic damage from aging. Studies have shown that introducing these cells can reset the body’s roadmap, repairing DNA damage. About six to eight weeks after infusion, the body’s repair mechanisms are reprogrammed, addressing degenerative changes, autoimmune diseases, neurodegenerative issues, and more. IV infusion is the best method we know so far.
06:09
Dafne Canales
Thank you so much, Dr. Layke, for introducing us to stem cells and exosomes.
06:14
Dr. John Layke
Of course. Listen, we’ll see you soon and hope you learned something.